Publications

Here is some of our work:

Camphor surfers exhibit collective bursting

Leoni M., Paoluzzi M., Dumaup C. A., Movagharnemati F., Nguyen-Leon L, Nguyen T., Eldeen S., Ahmed W. W. (2025)

Macroscopic active matter under confinement: dynamical heterogeneity, bursts, and glassy behavior in a few-body system of self-propelling camphor surfers

arXiv.2511.02506 [link]

Unsupervised AI can identify biofilm formation

Pérez Guerrero D., Manuel Antúnez Domínguez J., Vigne A., Midtvedt D., Ahmed W. W., Muiznieks L. D., Volpe G., Beck Adiels, C. (2025)

Latent Space-Driven Quantification of Biofilm Formation using Time Resolved Droplet Microfluidics

arXiv.2507.07632 [link]

Putting enzymes on DNA origami

Murphy, I., Bobilev, K., Hayakawa, D., Ikonen, E., Videbæk, T. E., Dalal S., Ahmed, W. W., Ross, J. L, Rogers, W. B. (2025)

A method for site-specifically tethering the enzyme urease to DNA origami with sustained activity

PLOS One20(4), e0319790. (2025) [link]

Inertia can hide activity

Arredondo, A., Calavitta, C., Gomez, M., Mendez-Villanueva, J., Ahmed, W. W., & Brubaker, N. D. (2024).

Inertia suppresses signatures of activity of active Brownian particles in a harmonic potential. 

Physical Review E109(3), 034405. (2024) [link]

An active bath transfers energy and can thin/thicken

Authors: Seyforth, H., Gomez, M., Rogers, W. B., Ross, J. L., & Ahmed, W. W.

Nonequilibrium fluctuations and nonlinear response of an active bath. 

Physical review research4(2), 023043. (2022) [link]

Stochastic forces show complex patterns in micro swimmers

Authors: Jones, C., Gomez, M., Muoio, R. M., Vidal, A., Mcknight, R. A., Brubaker, N. D., & Ahmed, W. W. (2021).

Stochastic force dynamics of the model microswimmer Chlamydomonas reinhardtii: Active forces and energetics. 

Physical Review E103(3), 032403. (2021) [link]

APS Irwin Oppenheim Award

Inertial active particles bounce and weave

Authors: Leoni, M., Paoluzzi, M., Eldeen, S., Estrada, A., Nguyen, L., Alexandrescu, M., Sherb, K., & Ahmed, W. W. (2020).

Surfing and crawling macroscopic active particles under strong confinement: Inertial dynamics. 

Physical Review Research2(4), 043299. (2020) [link]

Passive objects are centered just like the nucleus

Authors: Colin, A., Letort, G., Razin, N., Almonacid, M., Ahmed, W., Betz, T., Terret, M. E., Gov, N. S., Voituriez, R., Gueroui, Z. & Verlhac, M. H.

Active diffusion in oocytes nonspecifically centers large objects during prophase I and meiosis I. 

Journal of Cell Biology219(3). (2020) [link]

Small activity is still measurable (~kBT/s)

Authors: Eldeen, S., Muoio, R., Blaisdell-Pijuan, P., La, N., Gomez, M., Vidal, A., & Ahmed, W.

Quantifying the non-equilibrium activity of an active colloid. 

Soft matter16(31), 7202-7209. (2020) [link]

Myosin-II somehow affects cargo transport

Authors: Posey, D., Blaisdell-Pijuan, P., Knoll, S. K., Saif, T. A., & Ahmed, W. W. (2018).

Small-scale displacement fluctuations of vesicles in fibroblasts. 

Scientific reports8(1), 13294. (2018) [link]

Violation of FDT shows molecular motor kicking

Authors: Ahmed, W. W., Fodor, É., Almonacid, M., Bussonnier, M., Verlhac, M. H., Gov, N., Visco, P. van Wijland, F. & Betz, T.

Active mechanics reveal molecular-scale force kinetics in living oocytes. 

Biophysical journal114(7), 1667-1679. (2018) [link]

Dissipation spectrum quantifies injected energy

Authors: Fodor, É., Ahmed, W. W., Almonacid, M., Bussonnier, M., Gov, N. S., Verlhac, M. H., Betz, T., Visco, P. & van Wijland, F.

Nonequilibrium dissipation in living oocytes. 

Europhysics Letters116(3), 30008. (2016) [link]

Cells relax when illuminated

Authors: Knoll, S. G., Ahmed, W. W., & Saif, T. A.

Contractile dynamics change before morphological cues during fluorescence illumination. 

Scientific reports5(1), 18513. (2015) [link]

Cells are far from mechanical equilibrium

Authors: Ahmed, W. W., Fodor, É., & Betz, T.

Active cell mechanics: Measurement and theory. 

Biochimica et Biophysica Acta (BBA)-Molecular Cell Research1853(11), 3083-3094. (2015) [link]

Cells are fluids and solids

Authors: Ahmed, W. W., & Betz, T.

Dynamic cross-links tune the solid–fluid behavior of living cells. 

Proceedings of the National Academy of Sciences112(21), 6527-6528. (2015) [link]

Active fluctuations push the nucleus

Authors: Almonacid, M., Ahmed, W. W., Bussonnier, M., Mailly, P., Betz, T., Voituriez, R., Gov, N. S., & Verlhac, M. H. (2015).

Active diffusion positions the nucleus in mouse oocytes. 

Nature cell biology17(4), 470-479. (2015) [link]

Stretch increases active transport in neurons

Authors: Ahmed, W. W., & Saif, T. A.

Active transport of vesicles in neurons is modulated by mechanical tension. 

Scientific reports4(1), 4481. (2014) [link]

Alginate glues hydrogels to PDMS

Authors: Cha, C., Antoniadou, E., Lee, M., Jeong, J. H., Ahmed, W. W., Saif, T. A., Boppart, S. A., & Kong, H. (2013).

Tailoring hydrogel adhesion to polydimethylsiloxane substrates using polysaccharide glue. 

Angewandte Chemie International Edition52(27). (2013) [link]

Statistical mechanics reveals activity in vesicle motion

Authors: Ahmed, W. W., Williams, B. J., Silver, A. M., & Saif, T. A.

Measuring nonequilibrium vesicle dynamics in neurons under tension. 

Lab on a Chip13(4), 570-578. (2013) [link]

Pieces of the heart beat differently

Authors: De Souza, E. J., Ahmed, W., Chan, V., Bashir, R., & Saif, T. (2013).

Cardiac myocytes’ dynamic contractile behavior differs depending on heart segment. 

Biotechnology and bioengineering110(2), 628-636. (2013) [link]

Tension affects neuronal memory?

Authors: Ahmed, W. W., Rajagopalan, J., Tofangchi, A., & Saif, T. A.

Neuromechanics: the role of tension in neuronal growth and memory. 

Nano and cell mechanics: fundamentals and frontiers, 35-61. (2013) [link]

Tension increases clustering in synapses

Authors: Ahmed, W. W., Li, T. C., Rubakhin, S. S., Chiba, A., Sweedler, J. V., & Saif, T. A. (2012).

Mechanical tension modulates local and global vesicle dynamics in neurons. 

Cellular and molecular bioengineering5, 155-164. (2012) [link]

Cells dynamically reorient

Authors: Ahmed, W. W., Kural, M. H., & Saif, T. A.

A novel platform for in situ investigation of cells and tissues under mechanical strain. 

Acta biomaterialia6(8), 2979-2990. (2010) [link]

Cells align with mechanical strain

Authors: Ahmed, W. W., Wolfram, T., Goldyn, A. M., Bruellhoff, K., Rioja, B. A., Möller, M., Spatz, J. P., Saif, T. A., Groll, J., & Kemkemer, R. (2010).

Myoblast morphology and organization on biochemically micro-patterned hydrogel coatings under cyclic mechanical strain. 

Biomaterials31(2), 250-258. (2010) [link]

“Who needs mythology when reality is so unreal?”

Yanis Varoufakis in Another Now